More than 100 firefighters are tackling a blaze at a restaurant and office in Shoreditch, east London, according to Sky News.
London Fire Brigade told the television station that the ground floor and part of the first floor of the building in Tabernacle Street were burning.
According to the report, police say a number of roads in the area have been closed - including part of City Road south of Old Street, Bloomberg Square and Worship Street.
Officers are apparently also investigating reports that people were inside in the building.
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