London - People with a family history of cancer should seriously consider stopping drinking alcohol altogether, experts have warned.
The advice follows new research which shows a link between light drinking and the disease, particularly breast cancer in women.
The study, published in the British Medical Journal (BMJ), concludes that drinking just small amounts of alcohol increases the risk of cancer in women, and men who smoke.
The findings are based on data taken from two US studies, representing more than 135 000 people tracked over 30 years. Researchers from the Harvard TH Chan School of Public Health, Brigham and Women's Hospital, and Harvard Medical School, in Boston, Massachusetts, analysed the rate at which people succumbed to cancer.
After allowing for other risk factors such as obesity, smoking and family history of the disease, they found that light to moderate drinking - less than two drinks a day for women, and three to four drinks daily for men - is linked to an increased cancer risk.
Women who drink light to moderately face a 13 increased risk of cancer, regardless of whether they smoke. While the risk of alcohol-related cancers was also higher among men drinking at low levels, no association was found in men who had never smoked.
The risk for women is largely down to breast cancer. “Breast tissue might be more susceptible to alcohol than other organs. Probable explanations involve increased oestrogen and androgen levels,” says the research, funded by the US government.
The study stressed however that the increased risk was minimal. “Light to moderate drinking is associated with small and non-significant increased risk of overall cancer,” the study concludes.
Nevertheless, in an accompanying editorial, Dr Jürgen Rehm, of the Centre for Addiction and Mental Health in Toronto, said: “People with a family history of cancer, especially women with a family history of breast cancer, should consider reducing their alcohol intake to below recommended limits, or even abstaining altogether, given the now well established link between moderate drinking and alcohol-related cancers.”
His warning was echoed by Professor Sir Ian Gilmore, chair of the Alcohol Health Alliance UK: “This research confirms the results of previous studies showing that there is no such thing as a safe level of drinking when it comes to the risk of cancer.”
Dr Richard Roope, clinical lead for cancer at the Royal College of GPs, added that the study is a reminder of the link between alcohol and cancer: “We want our patients to live long and healthy lives.”
The Independent