Researchers have identified that an extract from avocado seeds exhibited anti-inflammatory properties in a laboratory study.
The team, including Joshua Lambert from Penn State, said that it represents a potential source for novel anti-inflammatory compounds that could be developed as a functional food ingredient or pharmaceuticals.
The researchers developed the extract over the last decade as a food colourant and it is not known whether the compounds responsible for the extract's vibrant orange colour play any role in its ability to inhibit the production of pro-inflammatory mediators, said Lambert.
To determine the anti-inflammatory properties of the avocado seed extract, the researchers used cell culture models and enzymes that are important in immune response and inflammatory diseases.
A class of immune cells called macrophages were grown in petri dishes and activated with a pro-inflammatory stimuli in the presence or absence of the avocado seed extract.