A herbal ingredient used in traditional Chinese medicines may help you to reduce your body weight, a new study has found.
The scientists were able to show that the herbal active substance, celastrol -- used in Chinese medicines -- leads to a significant weight loss and an improvement of diabetes in obese mice, Xinhua news agency reported.
The findings showed the celastrol specifically activates satiety centres in the brain, which play a central role in the control of body weight.
"Normally, those affected lose their satiety because the corresponding hormone leptin no longer works. The drug celastrol we investigated restores leptin sensitivity and hence satiety," said lead author Katrin Pfuhlmann from Helmholtz Zentrum Munchen - German Research Centre for Environmental Health.
The study, published in the journal Diabetes, observed a significantly altered eating behaviour in overweight animals.