The two year old appears alongside his rap legend father on the cover of the September issue of Harper's Bazaar, which celebrates the magazine's 'Bazaar icons 2018: The first families of music' edition.
The cover saw five-year-old North on the shoulders of the 'Gold Digger' hitmaker whilst Saint poses looking away from the camera.
Speaking to the publication, Kanye offered some advice to his and wife Kim Kardashian West's children, who also include seven-month-old daughter Chicago.
He said: "I hope my children never lose their confidence to society."
“I hope my children never lose their confidence to society.” — #KanyeWest with daughter #NorthWest and son #SaintWest on our September subscriber cover. Link in bio to see all the 2018 #BAZAARicons. Styling by @carineroitfeld Photography by @mario_sorrenti
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The black and white photo was shot by Mario Sorrenti and styled by Carine Roitfeld, but Kim and Kanye made the decision not to involve Chicago in the shoot.
Saint also appeared in a video shot by the magazine where he appeared wearing a 'Yeezus' shirt - referencing his father's hit 2013 album.
Other musical icons being honoured include; Bruce Springsteen who appeared with his daughter Jessica, Christina Aguilera and her two children - Summer Rain Rutler and Max Lion Bratman, and Lionel Richie appeared with daughter Nicole.
This isn't North's first major magazine cover, she appeared with Kim in Interview Magazine last year; she sat on her mother's lap, whilst she posed dressed as former First Lady Jackie Kennedy.