Durban - A woman died and five people were injured on Wednesday afternoon in a head-on collision on the M4 near Umdloti, KwaZulu-Natal, paramedics said.

Three people were critically injured, among them a 15-year-old boy, and two others were seriously injured including a one-year-old baby, Netcare spokesman Chris Botha said.

The patients were treated on the scene and hospitalised.

The cause of the accident would be investigated.