Australian researchers map immune response of patient to coronavirus

Graphic: Gerd Altmann/Pixabay

Graphic: Gerd Altmann/Pixabay

Published Mar 17, 2020

Share

Sydney - Australian researchers said on

Tuesday they have mapped the immune responses from one of

country's first coronavirus patients, findings the health

minister said were an important step in developing a vaccine and

treatment.

The coronavirus has infected more than 168,000 people

worldwide and killed at least 6,610, according to the World

Health Organization (WHO).

While the bulk of those infected experience only mild

symptoms, it is severe or critical in 20% of patients. The virus

mortality rate is about 3.4%, the WHO has estimated.

As scientists scramble to develop a vaccine, researchers at

Australia's Peter Doherty Institute for Infection and Immunity

said they had taken an important step in understanding the

virus.

By examining the blood results from an unidentified woman in

her 40s, they discovered that people's immune systems respond to

coronavirus in the same way it typically fights flu.

The findings help scientists understand why some patients

recover while others develop more serious respiratory problems,

the researchers said.

"People can use our methods to understand the immune

responses in larger COVID-19 cohorts, and also understand what’s

lacking in those who have fatal outcomes," said Katherine

Kedzierska, professor of microbiology and immunology at the

University of Melbourne, which took part in the research.

COVID-19 is the disease caused by the coronavirus.

As researchers monitored the Australian patient's immune

response, they were able to accurately predict when she would

recover.

Researchers did not name the patient, but said she was an

Australian citizen who was evacuated out of Wuhan, the epicentre

of the coronavirus outbreak in China.

Health Minister Greg Hunt described the development as

"world leading" and a major development in research on the

disease.

"It's about fast-tracking a vaccine by identifying which

candidates are most likely to be successful," Hunt told

reporters. "It's also about fast-tracking potential therapies

and treatments for patients who already have coronavirus."

At least a dozen drugmakers around the world are working on

vaccines or antiviral and other treatments for the

fast-spreading contagion.

But investment costs for vaccines could run as high as $800

million in a process that, even if accelerated, will likely take

more than a year until approval, according to executives from

companies involved in the effort. 

Reuters

Related Topics:

#coronavirus