Britain's Prince William, centre, arrives at the Yad Vashem Holocaust memorial in Jerusalem, Israel. Picture: Ariel Schalit/AP

Jerusalem — Prince William started his busy Israel tour Tuesday with a visit to Jerusalem's Yad Vashem Holocaust memorial.

William arrived Monday night in the first-ever official visit by a member of the British royal family to the tumultuous region London once ruled.

The Duke is set to meet two survivors who escaped Nazi Germany for the safety of Britain. The memorial has recognized Prince William's great-grandmother, Princess Alice, as part of the Righteous Among the Nations for her role in rescuing Jews during the Holocaust.

Yad Vashem said Princess Alice "hid the three members of the Cohen family - Rachel, Tilda and Michelle - in her palace in Athens during the Nazi occupation of Greece."

It said: "Princess Alice personally saw to it that the members of the persecuted Jewish family had everything they needed, and even visited them in their hiding place, spending many hours in their company."

Thanks to her, the Cohen family survived and today lives in France, it said.

The princess died in 1969 and in 1988 her remains were brought to Jerusalem.

Britain's Prince William arrives on a Royal Air Force plane at the Ben Gurion airport in Tel Aviv, Israel. His arrival Monday ends the monarchy's mostly hands-off approach to one of the world's most sensitive regions. Picture: Sebastian Scheiner/AP

In a private 1994 visit to Yad Vashem, Prince Philip, the Duke of Edinburgh, planted a tree there in his mother's honour.

Yad Vashem Chairman Avner Shalev is guiding Prince William through the memorial's exhibitions detailing the death of 6 million Jews systematically killed by Nazi Germany and its collaborators during World War II.

Though the trip is being billed as non-political and places a special emphasis on technology and joint Israeli-Arab projects, William will also be meeting with Israeli and Palestinian leaders and visiting landmark Jerusalem sites at the heart of the century-old conflict.

Britain's Prince William, centre, arrives at the Yad Vashem Holocaust memorial in Jerusalem, Israel. Picture: Ariel Schalit/AP

Three decades of British rule between the two world wars helped establish some of the fault lines of today's Israeli-Palestinian conflict, and Britain's withdrawal in 1948 led to the eventual establishment of Israel and Jordan.

Britain has since taken a back seat to the United States in mediating peace efforts, and the royal family has mostly steered clear of the region's toxic politics.

For the 36-year-old William, second in line to the throne, it marks a high-profile visit that could burnish his international credentials.