US President Joe Biden delivers remarks after a meeting with his Covid-19 Response Team on the White House campus in Washington. Picture: Jonathan Ernst/Reuters
US President Joe Biden delivers remarks after a meeting with his Covid-19 Response Team on the White House campus in Washington. Picture: Jonathan Ernst/Reuters

WATCH: Joe Biden, US officials sound alarm at signs of Covid-19 surge

By The Washington Post Time of article published Mar 30, 2021

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Lenny Bernstein, Ariana Eunjung Cha, Ben Guarino and Isaac Stanley-Becker

Washington – President Joe Biden and top health officials on Monday urged an impatient public to remain vigilant on the coronavirus, as daily case counts continued to rise, younger people replaced seniors in some US hospitals, and the US moved beyond the milestone of 30 million cases since the outbreak began.

Even as the nation's immunization programme continued to pick up speed and new research showed coronavirus vaccines are highly effective in real-world conditions, Biden said states should suspend reopening plans and governors who had rescinded mask mandates should reinstate them.

"Please, this is not politics," Biden said. "Reinstate the mandate if you let it down, and businesses should require masks as well. A failure to take this virus seriously – precisely what got us into this mess in the first place – risks more cases and more deaths."

Rochelle Walensky, director of the Centers for Disease Control and Prevention, went off script at a briefing Monday morning to demonstrate her alarm. Her words brought to mind a prescient warning from another CDC official, Nancy Messonier, director of the National Center for Immunization and Respiratory Diseases,who told Americans more than 13 months ago that their lives would dramatically change as the pandemic exploded in the US.

"I'm going to reflect on the recurring feeling I have of impending doom," Walensky said at a White House news briefing Monday. "We have so much to look forward to, so much promise and potential of where we are and so much reason for hope. But right now, I'm scared."

Troubling signals abounded Monday. Daily case counts continued their trend in the wrong direction. The seven-day rolling average of infections, which is considered the most reliable measure of daily case counts, rose for the seventh consecutive day, finishing just below 64 000, according to reports from state health departments analysed by The Washington Post.

Some hospitals reported admitting younger people with more severe disease. That is evidence that vaccines are protecting people older than 65 who once were most vulnerable but leaving the unvaccinated exposed. A new variant of the virus that is more contagious and causes more severe disease is taking hold across the country.

At Connecticut's Yale New Haven Health System, admissions of covid-19 patients ages 35 to 44 are up 41% in the past seven weeks, while admission of people 65 and older is down more than 70%. At Grady Memorial Hospital in Atlanta, inpatients older than 65 have largely disappeared, replaced by a younger population. And among the patients in Michigan's Henry Ford Health System, the median age has declined to 58, years younger than during previous surges of the virus.

"Younger people aren't vaccinated," said Tom Balcezak, chief medical officer at Yale New Haven, where 30% of people with covid-19, the illness that can be caused by the coronavirus, tested positive for the new variant that first was identified in the United Kingdom. "They're being exposed, if you will – blasted, if you will," by the variants.

As a result, more of them need intensive care than during earlier parts of the pandemic. "Last week we admitted and intubated a 21-year-old. That's really unusual for us," he said.

"Speed is of the essence here," Balcezak added. "Anything that slows vaccine distribution down is going to cause excess mortality."

Eduardo Oliveira, executive medical director for critical-care services for AdventHealth in central Florida, said the situation there is still significantly better than it was from November to January when the hospital had 70 or 80 patients on mechanical ventilation. Now there are about a dozen in the ICU, he said.

Oliveira said he has not seen any elderly patients coming to the ICU in weeks. Instead, he said, the new ICU patients are people he calls the "working middle aged", individuals in their 40s to 60s who typically have comorbidities.

"It is because of the reopening we are seeing more of this population," he said.

Greg Martin, chair of critical care at Grady Memorial Hospital in Atlanta and a pulmonology specialist at Emory University's medical school, said most patients 65 and older have disappeared, probably because of vaccinations, but younger people continue to stream in.

"It's not dropping the way it dropped before," Martin said.

Emory has not found that new variants are driving the trend in the Atlanta area. "It's still the typical things that have been circulating in Atlanta for months, not the variants we have seen out of the U.K., South Africa or Brazil," he said.

Martin said 10% to 15% of covid-19 patients who are hospitalised now are winding up in the ICU, a smaller percentage than in the past. That may be because younger patients have fewer underlying health conditions.

"I think it's not the illness that has changed. It's the people who are developing the illness."

Overall, hospitalisations are still declining despite the upticks in certain places, according to CDC surveillance data. But hospitalisation rates, like deaths, tend to follow jumps in case counts and could once again challenge the health-care system if a fourth surge of the pandemic develops.

The US trajectory mirrors trends a few weeks ago in Europe, where cases have risen sharply in France, Germany and Italy.

"Please hold on a little while longer. I so badly want to be done," Walensky said at the briefing. "I know you all so badly want to be done. We are just almost there, but not quite yet." The country does not have the "luxury of inaction" to prevent a fourth surge, she said.

Walensky, an infectious-diseases physician at Massachusetts General Hospital before her CDC appointment, continued: "I know what it's like as a physician to stand in that patient room gowned, gloved, masked, shielded and to be the last person to touch someone else's loved one, because their loved one couldn't be there."

Throughout the pandemic, older people have accounted for the majority of hospitalisations and deaths from a pathogen that preys on those with underlying health problems and weaker immune systems.

But now 73% of people older than 65 have received at least one shot, according to CDC data. Health authorities had hoped that younger people would continue to ward off the worst effects of the virus. Instead, the eventual toll appears to depend largely on how quickly vaccination can be carried out. More than 95 million Americans have received at least one shot as of Monday, CDC data shows.

"It will be a race between the vaccine and what's going on with the dynamics of the outbreak. And we can win this by just hanging in there a bit longer," Anthony Fauci, the nation's top infectious-disease specialist, said at Monday's briefing.

Biden told Americans that they stand at a precipice – and would only see the benefits of the nation's accelerating immunization campaign if they took a step back and renewed their commitment to basic mitigation strategies.

"With vaccines there's hope, which is a very good thing," he said. He promised that his administration would double the number of retail pharmacies offering coronavirus vaccines within the next three weeks, by which time 90% of adults in the United States will be eligible for the shots.

With additional locations established by April 19, virtually all residents will live within five miles of a vaccination site, Biden said, calling the immunization campaign the "American turnaround story". But there was no guarantee of a positive outcome, the president warned, saying conditions could easily become "worse, not better."

One bit of good news on Monday was the vaccine effectiveness study released by the CDC. It found that among 4 000 health-care personnel, police, firefighters and other essential workers, vaccines reduced the risk of infection by 80% after one shot and 90% after two.

The findings are consistent with clinical trial results and studies in Israel and the United Kingdom that have demonstrated how well the vaccines work.

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