LONDON - Swiss fifth seed and French Open runner-up Stan Wawrinka was knocked out of Wimbledon in the first round by Russia's Daniil Medvedev on Monday, losing 6-4, 3-6, 6-4, 6-1.
World number 49 Medvedev, making his Wimbledon debut, goes on to face Belgian qualifier Ruben Bemelmans for a place in the last 32.
It was Wawrinka's sixth first round loss at the All England Club, although his efforts were hampered by a left knee injury which required an ice pack at the changeovers.
It also meant that 33-year-old Wawrinka's hopes of becoming just the sixth man to complete the career Grand Slam were ended for another year.
What a moment for @DaniilMedwed...
A first-ever Grand Slam match win on Centre Court 😘 #Wimbledon pic.twitter.com/bYYqTpGqTL
— Wimbledon (@Wimbledon) July 3, 2017
Having lost in the first round at Queen's Club last month, Wawrinka's grass-court campaign amounted to two matches and two defeats.
For 21-year-old Medvedev, it was a first win at the Grand Slam level, coming on the back of an impressive grass court season.
He made the semi-finals in Eastbourne last week where it took Novak Djokovic to stop him, as well as the quarter-finals at 's-Hertogenbosch and Queen's.
Sealed with a kiss…
A moment @DaniilMedwed will never forget as he beats Stan Wawrinka 6-4, 3-6, 6-4, 6-1 on Centre Court. #Wimbledon pic.twitter.com/TmbWWiz9cO
— Wimbledon (@Wimbledon) July 3, 2017
"A year ago I was ranked 250. If someone told me in one year I would win on Centre Court I would tell you you are joking," said Medvedev, who kissed the grass of Centre Court to celebrate his victory.