Previous research on the consequences of early life stress and child maltreatment shows that these children will be more likely to develop a multitude of social and mental health problems. Teens and adults who experienced early adversity such as abuse, neglect or extreme deprivation are more likely to be socially isolated, spend time in jail, and develop psychological disorders including anxiety and depression.
Researchers have long puzzled over why early life stress is linked to such a wide variety of problems years later. Why do many of these problems emerge only in adolescence or even adulthood? These “sleeper effects” suggest early life stress might disrupt aspects of brain development that support key emotional and cognitive processes which normally promote positive social relationships and mental health.
Psychologists know that early life stress affects people’s ability to control or regulate their emotions and the brain regions that support these skills. For example, children who have experienced a lot of stress seem to have more difficulty containing negative emotions like anger or anxiety.
My colleagues and I carried out a study to investigate. Our findings suggest that, beyond emotion, two general learning mechanisms are also affected by early life stress – and these have the potential to explain long-term effects of childhood adversity.
Two types of social learning
My colleagues and I decided to focus on two cognitive skills that are fundamental to how people function socially in the world.
The first is the ability to learn and update associations between one’s own actions and the outcomes that result from them — what psychologists call “instrumental learning.” A very simple example would be learning that when I ring the doorbell, someone comes to the door.
But ringing a doorbell doesn’t always result in someone coming to the door – maybe no one is home. So links between actions and outcomes depend on the context. In this study, we were also interested in how stress affects the ability to update one’s knowledge when circumstances change — what psychologists call “cognitive flexibility.”
Say I’m telling my friend about the last ultramarathon I ran, giving her a mile-by-mile recap. My friend might be really engaged at first, so I’d form a positive association between my chosen conversation topic and her enthusiasm. But eventually she might start to get bored – I can be pretty long-winded when I talk about running.
Hopefully I’ll notice this shift – my association between me talking and her reaction will change – and I’ll wrap up my recap. But if I repeatedly fail to pick up on signals that my conversation partner is losing interest in what I’m talking about, she might start taking more rain checks on our coffee dates.
The circumstances around you, including other people’s reactions to your behavior, are continually changing, and it’s good for you to be able to recognise these changes and adjust your behavior accordingly. If not, you’ll have trouble developing healthy social relationships. It’s these skills our study focused on.
Looking for effects of stress in the lab
My colleagues and I brought teenage participants – half of whom had been physically abused by their caregivers in early childhood – into our lab to investigate how they did on particular cognitive tasks.
We first tested whether adolescents who had been abused in early childhood were as good as their peers at linking their actions in context to rewards and punishments.
The teens viewed pictures of everyday objects, like a shoe or a broom. These are neutral objects that aren’t inherently good or bad, so in this task participants had to learn through experience whether each picture was linked to a reward or a punishment. Each time they saw a picture, they had the option to either press a button or do nothing. If they pressed the button, they would either win points or lose points.
Halfway through the task, we switched things up. Because other studies found that children who experienced early life stress can have an especially hard time changing their responses, we were interested in our participants’ cognitive flexibility. Some of the pictures that had initially led to a reward now led to a loss and vice versa.
It turns out that teens who had been physically abused had more trouble with both parts of the task than their peers who had not been abused. Once they had learned the links between context, action and outcome, they had a hard time updating and adjusting their behavior when the situation changed – like when an event that had been linked to reward became linked to punishment, or vice versa.
While teens worked on this task, my colleagues and I used functional magnetic resonance imaging to measure which areas of their brains were active. When abused teens saw pictures that led to reward, the putamen and anterior cingulate cortex – two regions of the brain that help people learn associations between their actions and outcomes – were less active.