By Adam Taylor
Washington - As the Seychelles began to offer free coronavirus vaccinations early this year, President Wavel Ramkalawan told reporters that the country was planning to reach herd immunity within weeks.
It was an ambitious target for a small, geographically isolated island nation in the Indian Ocean. But with its economy heavily reliant on tourism, the country called in favours to attain a vaccine supply from regional allies, including India and the United Arab Emirates.
The effort initially seemed to be a success. The Seychelles stands as the most vaccinated nation on Earth, with more than 60% of its population fully vaccinated, more than other vaccine giants such as Israel and Britain, and almost twice the United States' rate of vaccination.
But that success has been undermined this week as the Seychelles has found itself with its largest number of new coronavirus cases per capita, and has been forced to reinstate a number of restrictions.
Though the number of new cases is relatively low - peaking at an average of just over 100 new cases a day - they are a big deal in a country with a population of less than 100 000. On a per capita basis, the Seychelles outbreak is worse than India's raging surge.
In a small country, even a small number of cases can be overwhelming.
"A spike in cases places an enormous burden on an already strained public health system," said Malshini Senaratne, director of Eco-Sol, an environmental consultancy firm in Seychelles.
With the country's main treatment centre for Covid-19 patients nearing capacity and doctors and nurses among the sick, the Seychelles announced the return of coronavirus restrictions, school closures and limited opening hours for shops and restaurants.
"These are an upward trend," said Public Health Commissioner Jude Gedeon at a media briefing Tuesday. "We do not know how long it will last, but this will depend on what measures are taken and how the new measures are respected."
The Seychelles situation is being watched all over the world for what it says about the effectiveness of vaccines.
"It is providing a critical case to consider the effectiveness of some vaccines and what range we have to reach to meet herd immunity," said Yanzhong Huang, a senior fellow for global health at the Council on Foreign Relations.
Huang noted that other nations that had vaccinated large proportions of their populations, including Israel and Britain, had seen significant drops in new daily cases.
Sherin Francis, chief executive of the Seychelles tourism board, said that while much of the population was vaccinated, there were pockets that were not.
Government data released this week found that of 1 068 active cases, around 65% involved residents who were either completely unvaccinated or had received only one dose.
Francis emphasized that even people who have been vaccinated can get infected. "Vaccines are very effective at preventing serious illness and death; they are less good at preventing infection," Francis said.
So far, the number of deaths in the Seychelles attributed to the virus is relatively low - 28 out of more than 6 000 cases. But the surge in new cases may also confirm that the vaccines being used in the country have comparatively low effectiveness.
Roughly 60% of the doses administered in Seychelles are vaccines made by the Chinese company Sinopharm that were donated to the Seychelles by the United Arab Emirates. The remaining doses are of the vaccine developed by AstraZeneca and produced by the Serum Institute of India.
In many ways, Seychelles government negotiations for vaccine supplies were savvy and speedy. But the country has ended up using two vaccines that appear to be less effective against symptomatic Covid-19.
The World Health Organization had recently estimated the efficiency of the Sinopharm vaccine at just over 78% for adults under 60, with little data on its success with older patients.
The UAE has asked some who received the Sinopharm vaccine to return for third doses, citing low immune responses, though officials said only a "very small number" need to do so.
Meanwhile, U.S. trials of AstraZeneca have found that the vaccine is 79% effective overall. Both vaccines are considerably lower in effectiveness than the vaccines developed by Pfizer and Moderna, which use mRNA technology and have reported effectiveness rates of around 95%.
Jennifer Huang Bouey, an epidemiologist who works with the Rand Corp., estimated that given what was known about the Seychelles' vaccine rollout and the vaccines used, less than 49% of the population could be assumed to have immunity conferred by vaccines.
"Less than half of the population is protected by the vaccine," Huang Bouey said. "It is still far below the community-level protection requirement."
"It's not surprising that they are not seeing a significant decline in cases," CFR's Huang said. "But what is surprising to me is that they've seen a significant increase in cases since late April."
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