The model and actress is set to front the upcoming new range - called Stellar Shine - which has been conceived by the makeup brand's creative and image director Peter Philips.
The updated formula - which looks to capture the "spectacular spirit of fashion" - is set to be launched in March, and it is the next step in Cara's collaboration with the company.
She is already the face of Dior's Capture Youth collection, which features skin care targeting the first signs of aging.
The announcement comes after the 26-year-old star - who will appear in both 'Carnival Row' and 'Fever Heart' next year - revealed she is planning to slow down and be more selective with her big screen roles.
She recently said: "It's really important now what scripts I choose and to wait for the right projects. I've definitely got better with [saying no]. I think we all get better at that with age."