A gang struck early at the Pick n Pay in Observatory, Cape Town, escaping with an undisclosed amount of cash.
According to News24, police spokesperson Captain FC van Wyk confirmed that a retail store had been robbed at about 6am on Friday by unidentified suspects.
"A group of men with firearms forced their way into the shop through a back entrance, tied all the workers up in a store room, and forced the key holder to open a couple of safes," he said.
"The suspects took an undisclosed amount of cash from the safes and fled in an unknown vehicle in the direction of the N2 highway."
No shots were fired and no one was injured, Van Wyk said.
A business robbery case was under investigation and the suspects were still at large, the police spokesperson added.
"Police crime scene experts are still on the scene, combing the area for clues."